Thursday Mar 20, 2025

The Weight Loss “Bermuda Triangle”: Are You Stuck In It?

Your genetics might be the key to lasting weight loss. Dr. Phyllis Pobee knows firsthand how frustrating it can be to do everything “right” and still struggle with weight. In this episode, Dr. Pobee joins Dr. Regina Druz to discuss how genetics for weight loss plays a bigger role than most people realize. Could your genes for weight loss be working against you? And if so, what can you do about it?

From nutritional genetics to hormones like cortisol and estrogen, Dr. Pobee breaks down why weight gain—especially for women over 30—isn’t just about diet and exercise. She shares how understanding your genetic profile can help you make smarter choices about food, exercise, and stress management. They also dig into the rise of weight loss medications like Ozempic and whether they truly solve the problem or just mask deeper imbalances.

This episode challenges the idea that weight loss is simply about willpower. If you’ve ever felt stuck, Dr. Druz and Dr. Pobee’s conversation might be exactly what you need to move forward with a strategy that actually works for your body.

Episode Breakdown:

00:00 Introduction

03:57 Hormonal Interplay in Weight Management

05:11 Estrogen and Heart Disease in Women

07:07 Genetic Variations and Hormonal Imbalances

08:41 Cortisol and Stress Management

10:21 Circadian Rhythm and Eating Habits

12:15 Measuring Cortisol Levels

17:54 Effective Stress Management Techniques

20:47 Testing Cortisol Levels

26:00 Hormonal Changes in Perimenopause and Menopause

30:56 Estrogen Dominance and Genetic Influence